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  1. Trough levels should be obtained within 30 minutes before the next scheduled dose. Weekly vancomycin levels should be obtained for long-term vancomycin use with stable renal function.

  2. Feb 22, 2023 · Do not restart vancomycin until the random/trough level is estimated or confirmed to be at/near 10-20 mg/dl. Allow sufficient time for drug clearance before restarting next dose.

  3. Understanding vancomycin levels : Nursing2025 - LWW

    In adults with normal renal function, the half-life of vancomycin is 6 to 12 hours. 2 If steady state occurs within five half-lives (that is, in 30 to 60 hours), a vancomycin trough before the fourth …

  4. Vancomycin: Parenteral dosing, monitoring, and adverse ... - UpToDate

    Sep 29, 2025 · Vancomycin is a glycopeptide antibiotic administered intravenously for treatment of patients with suspected or proven invasive gram-positive infections, including methicillin …

  5. Vancomycin Trough Monitoring | When & How to Dose

    A concise guide to interpreting vancomycin trough levels, timing the draw, and adjusting the dose safely especially in renal dysfunction.

  6. Selecting and interpreting trough levels: Always interpret trough level in context of timing of the preceding dose, particularly if the level appears to be much higher or lower than expected …

  7. Why & How to Monitor Vancomycin Troughs? - Medicine …

    Traditionally it is recommended to get trough doses to assess efficiency. Typically, we aim for Vancomycin trough levels between 10-20µg/mL (15-20 µg/mL for more severe infections).

  8. Vancomycin Level: Reference Range, Interpretation, Collection …

    Vancomycin is an antibiotic drug used to treat serious, life-threatening infections by gram-positive bacteria that are resistant to less-toxic agents. The reference range for vancomycin trough...

  9. What Is a Vancomycin Trough and Why Does It Matter?

    Aug 21, 2025 · A “trough level” refers to the lowest concentration of a medication in a patient’s bloodstream, measured just before the next dose is due. For vancomycin, this measurement …

  10. When ongoing vancomycin TDM is indicated, trough levels should be obtained once weekly. If the vancomycin regimen is changed in a patient with stable renal function, trough levels should be …