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  1. SUBSTANCE Definition & Meaning - Merriam-Webster

    The meaning of SUBSTANCE is essential nature : essence. How to use substance in a sentence.

  2. SUBSTANCE | English meaning - Cambridge Dictionary

    SUBSTANCE definition: 1. material with particular physical characteristics: 2. an illegal drug: 3. the most important…. Learn more.

  3. SUBSTANCE Definition & Meaning | Dictionary.com

    SUBSTANCE definition: that of which a thing consists; physical matter or material. See examples of substance used in a sentence.

  4. substance noun - Definition, pictures, pronunciation and usage …

    Definition of substance noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

  5. Substance - Definition, Meaning & Synonyms | Vocabulary.com

    Any material that possesses physical properties is called a substance. The word also refers to the gist or main idea of something. If you remember the main point of a lesson, you've got the …

  6. Substance - definition of substance by The Free Dictionary

    A drug, chemical, or other material (such as glue) that one is dependent on or uses habitually and that is often illegal or subject to government regulation: Which substance was he abusing?

  7. substance, n. meanings, etymology and more | Oxford English …

    substance is of multiple origins. Partly a borrowing from French. Partly a borrowing from Latin. Etymons: French substance; Latin substantia. What is the earliest known use of the noun …

  8. substance | meaning of substance in Longman Dictionary of …

    substance meaning, definition, what is substance: a particular type of solid, liquid, or g...: Learn more.

  9. substance - Wiktionary, the free dictionary

    Dec 14, 2025 · substance (countable and uncountable, plural substances) Study gives strength to the mind; conversation, grace: the first apt to give stiffness, the other suppleness: one gives …

  10. SUBSTANCE definition and meaning | Collins English Dictionary

    A substance is a solid, powder, liquid, or gas with particular properties. Ethylene glycol is a poisonous substance found in antifreeze. The substance that's causing the problem comes …