Studies of the molecular mechanisms of integrin endocytosis support a role for the alternative clathrin adaptor, disabled 2. Integrin trafficking during cell migration and cytokinesis has defined ...
A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated ...
Sevabertinib, targeting HER2 and EGFR mutations, received FDA breakthrough designation for HER2+ NSCLC, showing a 59% overall ...
The FDA and European Medicines Agency (EMA) have awarded orphan drug designation to CPI-008 (cRGD-ZW800-1), a novel ...
† WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow, G1 1XL, U.K. ‡ Fibrosis Discovery Performance Unit, ...
Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...
Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure and ...
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