A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

The human Y chromosome, responsible for determining male sex, finally has gotten an end-to-end examination. The Y chromosome is the smallest of the human chromosomes. “In the old time, people thought ...

A research team at The University of Osaka revealed that the loss of heterochromatin can cause a chain reaction leading to ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

WASHINGTON, Aug 23 (Reuters) - Scientists have taken an important step forward in understanding the human genome - our genetic blueprint - by fully deciphering the enigmatic Y chromosome present in ...