In drug discovery, various methods of lead generation exist that give researchers a starting point to develop drugs further and make them as efficacious as possible. High-throughput screening is a ...

The size of compound libraries amenable to standard virtual ligand screening (VLS) approaches is limited by the time and cost involved in screening. To keep pace with the increasing size of virtual ...

Generation of fragment screening libraries could enhance the analysis and application of natural products for medicinal chemistry and drug discovery, according to Griffith University's Professor ...

The better your library is designed, the better your chances of a successful screening hit. Given knowledge of the protein target, a focused approach to library design leads to far higher hit rates ...

Examination of libraries of biological information is increasingly seen as a potent tool in drug discovery. These collections may be genes, proteins, antibodies, RNAs, or chemical entities such as ...

Merck and HitGen have upsized their licensing agreement into a full-fledged, multiyear drug discovery collaboration, with plans to screen DNA-encoded libraries for new small-molecule assets. Under the ...

The identification of compounds that could be promising candidates for drug development has become easier following research by the Walter and Eliza Hall Institute's medicinal chemistry group. Dr ...

Synthego, the genome engineering company, today announced it received the Technology Award at the European Laboratory Research & Innovation Group’s (ELRIG) CRISPR in Drug Discovery 2020 meeting in ...