In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

Ribosomes are translational machineries that catalyse protein synthesis. Ribosome structures from various species are known at the atomic level, but obtaining the structure of the human ribosome has ...

Since the discovery of how DNA encodes genetic information, most research on the evolution of life has focused on genes. According to the 'selfish gene' theory, cells and organisms exist simply as ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

Last year, the Nobel Prize in Chemistry heralded work on DNA transcription, a cornerstone process in molecular biology in which a cell synthesizes a messenger RNA (mRNA) version of genomic DNA. For ...

As the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD), repeat expansions in the C9ORF72 gene spew a poisonous brew of abnormal RNAs and small ...