(Nanowerk Spotlight) Insulin is a rather small molecule (molecular weight 5.8 kD) and weakly charged in solution (isoelectric point 5.8) and therefore, low concentrations (<1 µM) are difficult to ...

An artificial system using a DNA-laced hydrogel can receive a chemical signal and release the appropriate protein, according to researchers. Further stimulation by the chemical signal continues to ...

Stanford researchers have developed a new biosensor with the ability to continuously detect and monitor the blood concentration of insulin and glucose in real time. The system, dubbed the Real-time ...

This schematic shows the secondary structure of two aptamers. The complex shapes formed by base pairing (black lines connecting G-C and A-T bases) allow aptamers to bind their targets with high ...

As with coffee or alcohol, the way each person processes medication is unique. One person's perfect dose may be another person's deadly overdose. With such variability, it can be hard to prescribe ...

Scientists simulate evolution in the lab by introducing mutations iteratively into biomolecules such as nucleic acids and selecting for desired properties. When carrying this process out specifically ...

Aptamers are short chains of nucleic or amino acids that are complementary to a specific target molecule and, hence, bind only with that molecule. This means that they are frequently DNA or RNA ...