A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has ...

Internationally recognized for its research institutes, including the Nano Life Science Institute (WPI-NanoLSI) and the Cancer Research Institute, Kanazawa University promotes interdisciplinary ...

Immune mechanisms can precipitate cerebrovascular thrombosis and hemorrhage, but the involvement of immunologic tolerance mechanisms in suppressing local vessel activation and prevention of stroke has ...

Explore how engineered extracellular vesicles can enhance antigen-specific regulatory T cells to improve immune response.

Sakaguchi's 1995 discovery of regulatory T cells revealed a complex immune tolerance system beyond central tolerance. Brunkow and Ramsdell identified the Foxp3 gene mutation in 2001, linking it to ...

Multiple sclerosis (MS) is a chronic immune-mediated disease characterized by the destruction of myelin sheaths, neuroaxonal damage, glial cell activation and formation of demyelinated plaques in the ...

LAPIX Therapeutics, Inc. (“LAPIX”), a clinical-stage biopharmaceutical company developing first-in-class, orally delivered immune-tolerance-restoring therapies, announced today that the first patient ...

The interplay between inflammation and immune suppression is central to host defense during infectious diseases. An appropriate inflammatory response is ...

A new class of engineered extracellular vesicles induces antigen-specific regulatory T cells, offering a targeted strategy ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich ...