Immunogenicity is a measure of the immune response to a biotherapeutic drug. It is a very relevant issue affecting not only the use of therapeutic protein drugs such as mAbs but also peptides, enzymes ...

Assessing immunogenicity is a cornerstone of modern drug development, especially for biologics and vaccines. Understanding how the immune system interacts with therapeutic agents is essential to ...

A drug-induced immune response can significantly alter the safety and efficacy of biotherapeutic drugs. Hence, early testing and prediction of potential immunogenicity and allergenicity caused by ...

Assessment of immunogenicity is an important component of drug safety evaluation in preclinical, clinical and postmarketing studies. Biopharmaceuticals currently employed in the clinic exhibit various ...

BALTIMORE--(BUSINESS WIRE)--Sapio Sciences, the science-aware™ lab informatics platform, today announced the addition of new immunogenicity bioanalysis features to its industry-leading lab informatics ...

With some medical interventions, immunogenicity is the whole point—hence the “good” immunogenicity provoked by vaccines. Immunogenicity is much to be avoided, however, when biotherapeutics are ...

The use of biologic-based therapeutics has revolutionized our ability to treat complex diseases such as cancer- and autoimmune-related disorders. Biologic-based therapeutics are known to generate anti ...

Sapio Sciences, the science-aware ™ lab informatics platform, today announced the addition of new immunogenicity bioanalysis features to its industry-leading lab informatics platform. These new ...

This is a preview. Log in through your library . Journal Information Founded in 1904, The Journal of Infectious Diseases is the premier publication in the Western Hemisphere for original research on ...

From the 1980s, therapeutic protein drugs — monoclonal antibodies, proteins, antibody-drug conjugates, bispecific antibodies, etc. — have been widely employed in the treatment of HIV, tumors and other ...