Breathing disorders are common in the U.S. with conditions like COPD affecting some 7% of the population and asthma affecting another 10%. Digestive conditions like GERD, acid reflux, Celiac disease ...
The UAB Gregory Fleming James Cystic Fibrosis Research Center is a university-wide interdisciplinary research center funded by the National Institutes of Health, the Cystic Fibrosis Foundation and ...
Cystic fibrosis is a genetic disorder that affects roughly 40,000 Americans. The condition is caused by a mutation in the patient's cystic fibrosis transmembrane conductance regulator (CFTR) gene, ...
PF pathogenesis involves alveolar epithelial cell injury, profibrotic mediators, and dysregulated non-coding RNAs, complicating disease management. Current treatments, including pirfenidone and ...
Iron metabolism imbalance and ferroptosis are central to PF pathogenesis, offering new therapeutic targets. Ferroptosis links oxidative stress, iron overload, and fibrotic remodeling, affecting key ...
Today (September 11), the Lasker Foundation announced this year’s award winners. Jesús (Tito) González, an ion channel biologist formerly at Vertex Pharmaceuticals, Paul Negulescu, a cell biologist at ...
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