New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...

One of the ways scientists are trying to improve cancer treatments is by better equipping the body's own immune system to ...

The results of the study could improve immunotherapy treatment for patients with colorectal and other barrier-tissue cancers.

TangGene names former GSK SVP Catherine Sohn as Senior Strategic Advisor, strengthening leadership as it advances a first-in-class in-vivo CD8⁺ Treg therapy. TangGene’s in-vivo CD8⁺ Treg approach has ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...