JSTOR Daily

Par3/Par6 Polarity Complex Coordinates Apical Ectoplasmic Specialization and Blood: Testis Barrier Restructuring during Spermatogenesis

The Par3/Par6/aPKC and the CRB3/Pals1/PATJ polarity complexes are involved in regulating apical ectoplasmic specialization (ES) and blood-testis barrier (BTB) restructuring in the testis. Par6 was a ...
Nature

Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole

Before neurogenesis, the neural tube wall consists of only one cell type, the neuroblasts, from which all neurons and glial cells derive. Neuroepithelial cells form a single-cell-layered ...
科学技術振興機構

[Sachiko Tsukita] Elucidation of a novel unified epithelial system defined by the reciprocal regulation of cell-cell adhesion and the apical cytoskeleton and its use for ...

Epithelial cells adhere tightly to each other via tight junctions (TJs), thereby forming epithelial cell sheets. A major target of this project is the “apical complex,” a system composed of the TJ, ...
JSTOR Daily

Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA

Helicobacter pylori translocates the protein CagA into gastric epithelial cells and has been linked to peptic ulcer disease and gastric carcinoma. We show that injected CagA associates with the ...